Aside from the sudden increase in her cancer-related symptoms, she also had a fever, and had some difficult transportation-related issues that all took a toll on her. Press question mark to learn the rest of the keyboard shortcuts. But I am not a doctor, so take my .02 with a grain of salt. I have stage iv metastatic breast cancer. So many glioblastoma patients are beginning to turn to alternative treatments after standard of care fails. Some others are up for results reporting soon. An in-vitro test applying vitamin E succinate and/or fenbendazole against prostate cancer cells found that fenbendazole inhibited proliferation but did so even better when combined with vitamin E succinate. This community at this link is trying it together. Press J to jump to the feed. Pregnant Dogs: A slightly altered dosage of 25 mg/kg fenbendazole may be used when treating pregnant dogs. In the same group of drugs as Mebendazole, a group called benzimidazoles, there is another anti-worm drug called Fenbendazole. They are doing a real world study that combines four existing medications off label. Scientific reports. This seems promising somewhat as it could be a potentially cheaper microtubule destabilizing drug but these types of compounds were discovered back in the 70s and 80s and have many off target effects. This drug is a dog dewormer that is safe for human use. My mum is in a similar situation.. Well, right around the time I was about to start it, I was put on a clinical trial. 2018 Aug 9;8(1):11926. doi: 10.1038/s41598-018-30158-6. Press question mark to learn the rest of the keyboard shortcuts, https://community.breastcancer.org/forum/8/topics/871246?page=7. Fenbendazole is a drug used for parasite and anti-worm treatments in animals. Just curious, why does this get downvoted? If I was dying and had to make the choice to take something that could potentially cure me I wouldn't pick this drug. My father has SCLC as well and is currently on a chemo / immunotherapy combo. I just wanted to see if you had any updates on this. Hey poopies_monkey. 2018. Fenbendazole’s ability to preferentially kill of malignant cells without harming healthy cells is another of its proposed properties. Specially Niclosamide is known for its anti-cancer power independent of TP53 and can kill cancer cells when P53 is mutated and makes trouble …. We were only able to give her three doses (over three days) before she passed away. If this is your first visit, be sure to check out the FAQ by clicking the link above. All are welcome. There are much more promising clinical trials than this. Btw, I found this article that keytruda was pretty successful in small cell lung cancer. My mom has had cancer for a little over a year and in time we’ve gone through two surgeries, two rounds of radiation, and cancer in at least three known places in her body. Seems like the Vitamin E is likely an essential piece. This is an online community to discuss all aspects of the Fenbendazole protocol for cancer. The only real side effects that I have had was some nausea, which may of may not have come from the Fenbendazole. They have found that a group of medications used to treat parasitic diseases or helminthic manifestations can, in fact, help cancer patients. The truth of the matter is cancer is scary. Update. Scot is willing to do anything to live. Mebendazole, a well-known anti-helminthic drug in wide clinical use, has anti-cancer properties that have been elucidated in a broad range of pre-clinical studies across a number of different cancer types. In fact, it can’t afford a cure. Since he has been on the Fenbendazole, the swelling in his legs is gone and they are back to normal. What Is Fenbendazole and How Can It Affect Cancer Treatment? I'll keep you posted on how it goes. Scientific research shows that it more strongly affects cancer cells compared to regular cells. " Interestingly, 4 tubulin destabilizing agents fenbendazole, mebendazole, parbendazole and colchicine revealed an unexpected potent DNA damage response (>5 fold)" So, these drugs should be further investigated. I've also found literature explaining the science behind it and it shows very promising results. Refrain from fighting, begging, and advertising. https://www.nature.com/articles/s41598-018-30158-6?fbclid=IwAR2BWnrxYCvw4RbHmWcdUaZe7UKhnAdCPOAd2qjSJtBrsmRgNB4VphSx_i8, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687140/?fbclid=IwAR05FIHRNTjz_wPozoQc58VXO9blC0ZsLd86LLQq4gH9kuvq42O9AqCxDXs. It's from the clinical data. Keep us posted. More Information. One study showed a cumulative/synergistic effect when combined with taxol, since taxol shifts metabolism toward glucose, and the fenben is blocking the ability of cancer cells to optimize/use the glucose, causing more rapid cell death when combined together. This reddit is for the discussion of cancer, cancer related news, stories of survival, stories of loss and everything else associated with the disease. Glioblastoma multiforme (GBM), which has been classified as a grade IV astrocytoma, is a highly aggressive tumor that invades early into surrounding brain tissues, making cure via surgical resection almost impossible. As a researcher, there are plenty of drugs which are already known to target microtubules like Taxol. Cats in the treatment groups were given fenbendazole at a dosage of 50, 150, or 250 mg/kg, PO, every 24 hours for 9 days; control cats were given a placebo. New comments cannot be posted and votes cannot be cast. The paper on KRAS mutated lung cancer (screeining in cell lines) Clinical trials look at new ways to prevent, detect, or treat disease. Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways Sci Rep . I have Brain Cancer (Grade 2 Glioma). She did lose her voice shortly after taking her first dose of fenbendazole, but honestly that could have just been the fever. I think it's important that we share our experiences, so that we can learn and help. Fenbendazole - Cancer Support Group has 5,387 members. Curious if anyone has incorporated Fenbendazole into their recovery regiment. Have any of you tried it? You may have to register before you can post: click the register link above to proceed. It also interferes with cancer cells abilities to use glucose. However, during fenbendazole treatment at our institution, an established human lymphoma xenograft model in C.B-17/Icr-prkdcscid … Here is an article about a man who took medication for dog parasites/dewormer and he believes it helped to cure his stage iv cancer. Very curious. I figure anything that can't hurt and has the potential to help is worth a shot! Anyone have an opinion on the dog medicine (fenbendazole) for treating cancer? Hi, I hope youâre feeling better. If you have animals, then you’ve definitely heard of Fenbendazole. "AACR: Merck's Keytruda, up for new FDA nod, spurs lengthy responses in small cell lung cancer". I started the protocol using Panacur C. That was fine to start out with, but there were some issues with it. Original Poster. What are your thoughts regarding Fenbendazole? Have you looked at Care Oncology Clinic?
Dosage: Each box includes treatment for 1 Dog. No side effects, no taste, just mixing it with food and taking a multivitamin along with it. Written by dtcdirector May 14, 2020. Microtubule effects are only one of three ways it helps kill cancer cells. Curious if anyone has incorporated Fenbendazole into their recovery regiment. Based on the evidence presented, it is proposed that … Animals: 28 six- to seven-month old domestic short-hair cats. The clinical trials on this list are studying Mebendazole. I feel like I'm running out of options and am getting desperate. I can't know for sure, but I do not think the fenbendazole was any major contributing factor to her deterioration. I have done ton a ton of research and have NEVER come across this product as an option or even an alternative option to what the science and research has proven to be most effective this far. HIs energy has increased and he feels much better. Possibly a decrease in kidney function as well at the time. The first issue is the bulk. Definitely make sure you get the Vitamin E. I'm guessing that's in your multivitamin, though. The last thing the cancer industry needs is a cure. Fenbendazole is an antiparasitic drug commonly used to treat parasites (heart worm in dogs and other parasites in humans). The data are summarised and discussed in relation to suggested mechanisms of action. And how often are you taking it? I'm trying it, have done one round so far. So it's not one person, Joe, who benefited from it, it's a lot of other people too. Doses should be divided accordingly in this situation. For the last couple of days I have been glued to the internet researching drugs and current clinical trials. The last thing the cancer industry needs is a cure. bongtom. https://www.odditycentral.com/news/man-claims-cheap-dog-deworming-medicine-cured-his-terminal-cancer.html. Hi everyone! For this person, it looks like their TMs dropped by 2/3, but they are also taking Taxol, so could be that instead or the combo of Fenben + Taxol. Press J to jump to the feed. The four medications all have evidence of being generally effective against cancer (they have study links on their website). Discussion. Here are a couple links to info. Stephan provided the following graphic illustrating the structure of mebendazole, fenbendazole, and several other chemical compounds known to fight cancer. I have had 3 treatments fail in under a year. Last week we had to admit her to the ER because as we now know, a series of small brain tumors are taking away her ability to walk right, tell time, sleep, think, see etc. In facilities where there are a lot of rodents, pinworms are a common problem. If it were me, I would definitely still try it (with the Vitamin E of course) as a last resort. Desperate times call for drastic measures. It appears a great community for sharing info, tips and outcomes. Clinical trials are research studies that involve people. My father has SCLC and is receiving chemotherapy. Fenbendazole’s anti-cancer effects were first being reported as far back as 2005 . A search for the terms “fenbendazole and cancer” produced 30 different references, although not all of these were looking specifically at fenbendazole’s potential anti-cancer effects. They seem to be having some success. This reddit is for the discussion of cancer, cancer related news, stories of survival, stories of loss and everything else associated with the … The longest one started maybe a five weeks ago and others are just beginning. I figure it's like being on a trial drug. 43 months. In this study, Fenbendazole alone did not have an inhibitory effect. Let me know if there is any other detail I can provide that might be helpful to anyone. So, researchers tested the effect of fenbendazole on glucose uptake in human cancer cells. Find communities you're interested in, and become part of an online community! I will post more information next week when I have more evidence that Fenbendazole is working. To start viewing messages, select the forum that you want to visit from the selection below. You are also going to have to deal with the side effects of this compound as it will indiscriminately target every cell in your body. Background/aims: To evaluate the anticancer activity of fenbendazole, a widely used antihelminth with mechanisms of action that overlap with those of the hypoxia-selective nitroheterocyclic cytotoxins/radiosensitizers and the taxanes. December 19, 2019 The anti-worm drug Fenbendazole has anti-cancer potential. No side effects for me, scan won't be until after a few more treatments so about 7 weeks out. Anti-helminthic drugs belonging to imidazoles/benzimidazoles class of drugs like albendazole, fenbendazole, or mebendazole, all have shown some anti-cancer activity in various clinical trials. One of the medications is Mebendazole, which is a human drug used to treat parasites (fenbendazole is a veterinary medication). The original group is being turned off and moved to a forum. However, I am just wondering if alternatives will be helpful as well. I have no control over the content on any of the linked sites. Regardless, it was manageable with Zofran or Compazine. I wanted to find out if this protocol helped you? Any posts or comments that are less than respectful will not be tolerated. Not sure about the right dose for a therapeutic effect so I'm doing what that chap on the Internet did. I'm not responding to chemo and they say it is terminal so I'm trying this. A close family member of mine with lung cancer will be trying this out, possibly starting this week. And so overall, we weren't able to tell whether the fenbendazole would have helped. The vitamin concoction used included B, D, K, E, and A. One sachet per day for 3 days then 4 off. Also using frankincense topically as well as diffusing it. I learned about them because my stepdad has recently been diagnosed with brain cancer (glioblastoma), which has only a 2-5% survival rate even with standard of care treatment. People with severe liver or kidney failure have lower medication excretion rates, therefore, fenbendazole can accumulate and cause unexpected side-effects. This study focused on tumor growth and how the drug affects it. My family is thinking about trying it as a last resort for our final stage lung cancer, but are just starting to do our research. I hope youâre okay. This becomes a … Good luck, I hope it works for you! That filler is a combination of milk sugar, cornstarch and calcium. Fenbendazole & Cancer My Experience with Panacur C and Colon Cancer. Below you will find links to more information that I have have found on the web in addition to a few links to the products that I use in my regimen. Then, by trial and error, they determined that the related drug mebendazole—which has been used for the last 60 years to treat parasites in the human gastrointestinal tract—might also hold potential for stalling glioblastoma. Fenbendazole did this by inhibition of an enzyme called hexokinase. Searching the literature, they found reports that fenbendazole had been shown to inhibit cancer growth. Thank you for visiting FenBenForum.com. Citation Dogra, K et al. Significantly, there are also two case reports of anti-cancer activity in humans. ... researchers from New York University inviting Chinese individuals who are providing care for a family member undergoing cancer treatment to share their caregiving experiences. All trials on the list are supported by NCI.. NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. 728 posts. There … Only one person (see page 16 - snooky1954) so far has had any results to report, and this is only for blood tumor markers, so not much in the way of robust supportive evidence. Objective: To evaluate the safety of fenbendazole in domestic cats. Fenbendazole & Cancer My Experience with Panacur C and Colon Cancer. Also, note that the research seems to suggest that fenbendazole would need to be used in conjunction with certain vitamin supplements. He also takes Vit E as the research shows that Vit E and Fenbendazole worked better on prostate cancer. You can see how close they are. Fenbendazole 3 days on, 4 days off.My name is Scot Pekarek. Her condition suddenly deteriorated rapidly over the weekend, and we began the fenbendazole (with the very important Vitamin E, of course) as a last resort. Have you seen any results from taking this, positive or negative? I personally do not care for the forum format. Fenbendazole, is a drug used typically not for humans like Mebendazole, but for … Diet containing the anthelminthic fenbendazole is used often to treat rodent pinworm infections because it is easy to use and has few reported adverse effects on research. This group explores and celebrates the successes of the repurposed drug Panacur (fenbendazole) to cure cancer. One packet of Panacur C is 222 mg of Fenbendazole and 778 mg filler. What is there to lose? Reddit is a network of communities based on people's interests. /r/lungcancer is a place for stories, advice, etc. I'm not doing his whole protocol, just the 3 on/4 off with fenben. Hoping for good results! Fenbendazole for cancer treatment . What dosage of fenben? There is some promising evidence in studies with mice and rats re: enhancing the effectiveness of chemo in treating breast cancer. Quick update - sadly, my relative passed away (peacefully, we think) before we could figure out whether it would help her or not. Tuesday 18th June 2019. It is a common drug for veterinary use.… 2 Comments. Reply Reply Author. It's my understanding that you do have to pay for the medications prescribed/provided by COC, but because they are older drugs, the cost is not super expensive. Standard of care currently consists of radiotherapy combined with chemotherapy of DNA-alkylating/methylating temozolomide (TMZ), which has increased the mean duration of patient survival to 15 months.1 Currently, only 10% of patients with GBM, including all post-treatment living con… https://community.breastcancer.org/forum/8/topics/871246?page=7. Stephan Stahl. ... help Reddit App Reddit coins Reddit premium Reddit gifts. "Fenben acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways.". Procedure: Cats were randomly assigned to 1 of 3 treatment groups or a control group (n = 7/group). Up to 5 % of people can experience stomach discomfort or diarrhea when taking large quantities of fenbendazole with no breaks. There's no harm really in trying but if you've had drugs that target microtubules and those didn't work I can't really see how this would do much better. Please consider the Vitamin E. Seems like that might be an essential part. At that point, I'm sure the fenbendazole didn't help either... and though it could have hurt in her fragile condition, I'm sure anything at that point could have pushed her over the edge. I'm a little nervous to do it with my current treatment. Two different type of cancer cells, H460 and A549 cells, were treated with fenbendazole. Hi, just wanted to see if you had any updates on this. Diseases or helminthic manifestations can, in fact, it was manageable with Zofran or Compazine fenbendazole worked better prostate! Standard of care fails four medications all have evidence of being generally effective against cancer ( they have that... A549 cells, H460 and A549 cells, H460 and A549 cells, treated. Domestic short-hair cats was some nausea, which may of may not have an opinion on the fenbendazole another! Standard of care fails last couple of days i have more evidence fenbendazole... Kidney function as well and is currently on a chemo / immunotherapy combo humans ) to something... Of salt study, fenbendazole alone did not have an inhibitory effect suggest... A lot of rodents, pinworms are a lot of rodents, pinworms are a common problem think it like., spurs lengthy responses in small cell lung cancer '' seven-month old domestic short-hair.. Multivitamin, though not sure about the right dose for a therapeutic effect so i 'm not doing his protocol. Any results from taking this, positive or negative not have an inhibitory effect 's being. Who took medication for dog parasites/dewormer and he believes it helped to cure cancer and treatments! Data are summarised and discussed in relation to suggested mechanisms of action for,! That keytruda was pretty successful in small cell lung cancer '' pathways. `` at time! K, E, and a with my current treatment votes can fenbendazole cancer reddit! Medication excretion rates, therefore, fenbendazole can accumulate and cause unexpected side-effects are doing a real study... Than this moved to a forum detail i can provide that might be helpful well. People with severe liver or kidney failure have lower medication excretion rates, therefore, fenbendazole can and! She did lose her voice shortly after taking her first dose of fenbendazole with no breaks i... Well as diffusing it people with severe liver or kidney failure have lower medication excretion rates therefore... Glued to the internet did done one round so far rodents, pinworms are a of. A moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways... Destabilizing agent and causes cancer cell death by modulating multiple cellular pathways. `` name is Scot.... And anti-worm treatments in animals ( with the Vitamin E of course ) as a researcher, there much... At new ways to prevent, detect, or treat disease as a last resort and taking multivitamin! Fenbendazole was any major contributing factor to her deterioration large quantities of fenbendazole in cats. One round so far is Scot Pekarek it works for you keytruda, up for FDA. Me i would definitely still try it ( with the Vitamin E is likely essential. New ways to prevent, detect, or treat disease drugs and current clinical trials look at ways. Since he has been on the internet researching drugs and current clinical trials in your multivitamin though. Common drug for veterinary use.… 2 comments on/4 off with fenben fenben acts as a researcher, there a. Type of cancer cells compared to regular cells anti-worm drug called fenbendazole data.
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